Table 3.

Impact of NICE guidelines

	Diagnostic yield of CRC	Diagnostic yield of IBD	Overall diagnostic yield	OR
CRC NICE criteria positive (n=592)	3% (n=17)	n/a	n/a	7.71 (95% CI 1.77 to 33.56, p=0.0064)
CRC NICE criteria negative (n=524)	0.4% (n=2)	n/a	n/a
IBD NICE criteria positive (n=517)	n/a	9% (n=48)	n/a	3.5 (95% CI 1.99 to 6.17, p<0.0001)
IBD NICE criteria negative	n/a	2.8% (n=17)	n/a
CRC +IBD NICE criteria positive (n=899)	n/a	n/a	15% (n=133)	1.44 (95% CI 0.919 to 2.278, p=0.11)
CRC +IBD NICE criteria negative (n=217)	n/a	n/a	13% (n=28)

CRC, colorectal cancer; IBD, inflammatory bowel disease; n/a, not applicable; NICE, National Institute for Health and Care Excellence.