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. 2020 Apr 17;86(9):e00102-20. doi: 10.1128/AEM.00102-20

TABLE 2.

Mutations identified in genes associated with AMR or the response to stress through WGS analysis of Salmonella antibiotic-resistant variantsa

Strain No. of genes with mutations
AMR-related genes
Stress response-associated genes
Complex Del Ins MNP SNP Total Gene Type Gene Type (mutation)
1-EVOL 1 4 4 0 21 29 crl Del (Ser35fs)
rcsC SNP (Ser394Leu)
ptsJ SNP (Pro138Ser)
cytR SNP (Asn219Tyr)
recE-like gene Complex (SerIleTrp511ArgIleArg)
recE-like gene SNP (Ala117Thr), SNP (Val119Ala)
2-EVOL 1 1 5 0 46 53 gyrA SNP (Met86Ile) uvrB SNP (Asn624Lys)
zntA SNP (Leu43Pro)
3-EVOL 0 2 1 0 18 21 gyrA SNP (Pro83Ser) crl Del (Ser35fs)
dacB SNP (Ala161Val) hnr SNP (Leu102Val)
soxR SNP (Val20Leu)
4-EVOL 1 2 1 0 19 23 rpsL SNP (Lys88Glu) crl Del (Ser35fs)
dacB SNP (Ala161Val) hnr SNP (Leu102Val)
gppA Complex (IlePro125MetPro)
a

Complex, the genome contains two or more of the following mutation types: deletion (Del), insertion (Ins), multiple nucleotide polymorphism (MNP), and single nucleotide polymorphism (SNP).