Table 2.
The Diagnostic Performance of US, MRI, and US+MRI Under Different Definitions of pCR
| Measures | pCR | Sensitivity (95% CI) | Specificity (95% CI) | Accuracy (95% CI) | PPV (95% CI) | NPV (95% CI) |
|---|---|---|---|---|---|---|
| US | ypT0/is | 36.2 (31.6–40.9) | 90.2 (88.1–92.4) | 71.2 (68.6–73.8) | 67.3 (61.1–73.4) | 71.9 (69.0–74.8) |
| ypT0 | 38.2 (33.1–43.3) | 89.0 (86.9–91.2) | 73.7 (71.1–76.2) | 60.1 (53.7–66.5) | 76.9 (74.2–79.6) | |
| z | 0.5 | 0.9 | 1.4 | 1.7 | 2.4 | |
| p | 0.627 | 0.382 | 0.178 | 0.094 | 0.015 | |
| MRI | ypT0/is | 44.4 (39.4–49.5) | 92.9 (90.9–94.9) | 75.6 (72.9–78.2) | 77.7 (72.1–83.3) | 75.0 (72.0–78.0) |
| ypT0 | 47.2 (41.7–52.8) | 91.0 (88.9–93.1) | 77.9 (75.4–80.4) | 69.2 (63.0–75.4) | 80.1 (77.4–82.9) | |
| z | 0.7 | 1.4 | 1.2 | 2.1 | 2.4 | |
| p | 0.510 | 0.160 | 0.251 | 0.036 | 0.015 | |
| US+MRI | ypT0/is | 22.5 (18.1–26.9) | 98.0 (96.9–99.1) | 70.5 (67.6–73.4) | 86.8 (79.9–93.8) | 68.8 (65.7–71.8) |
| ypT0 | 24.3 (16.4–29.2) | 97.1 (95.9–98.4) | 74.7 (72.0–77.5) | 79.1 (70.8–87.5) | 74.3 (71.4–77.2) | |
| z | 0.5 | 1.0 | 2.1 | 1.4 | 2.5 | |
| p | 0.586 | 0.302 | 0.036 | 0.167 | 0.011 |