Table 3.
Association Between Necroptosis Signaling with Pathological Parameters
| Parameters | Total n=50 |
MLKL Score | p value | ||
|---|---|---|---|---|---|
| Low (1–4) | Medium (5–8) | High (9–12) | |||
| ERα | 0.094 | ||||
| Negative | 19 | 8 | 8 | 3 | |
| Positive | 31 | 12 | 6 | 13 | |
| PR | 0.125 | ||||
| Negative | 28 | 10 | 11 | 7 | |
| Positive | 22 | 10 | 3 | 9 | |
| HER2 | 0.193 | ||||
| ≤2+ | 21 | 9 | 8 | 4 | |
| 3+ | 29 | 11 | 6 | 12 | |
| Ki67 | 0.018 | ||||
| ≤30% | 28 | 16 | 5 | 7 | |
| >30% | 22 | 4 | 9 | 9 | |
Abbreviations: ERα, estrogen receptor alpha; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2; MLKL, mixed lineage kinase domain-like protein.