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. 2020 Apr 16;13:3165–3176. doi: 10.2147/OTT.S246899

Table 3.

Association Between Necroptosis Signaling with Pathological Parameters

Parameters Total
n=50
MLKL Score p value
Low (1–4) Medium (5–8) High (9–12)
ERα 0.094
 Negative 19 8 8 3
 Positive 31 12 6 13
PR 0.125
 Negative 28 10 11 7
 Positive 22 10 3 9
HER2 0.193
 ≤2+ 21 9 8 4
 3+ 29 11 6 12
Ki67 0.018
 ≤30% 28 16 5 7
 >30% 22 4 9 9

Abbreviations: ERα, estrogen receptor alpha; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2; MLKL, mixed lineage kinase domain-like protein.