Extended Data Table 2. TG domain annotation.
| Region (residue range) | Region name | Domain | Domain type | Template for homology model (PDB ID) |
|---|---|---|---|---|
| 31-92 | NTD | A | type-1 TG repeat | 1ICF.I |
| 93-160 | NTD | B | type-1 TG repeat | 1ICF.I |
| 161-297 | NTD | C | type-1 TG repeat | 1ICF.I |
| 298-358 | NTD | D | type-1 TG repeat | 1ICF.I |
| 359-620 | NTD | E | helical | de novo |
| 621-658 | Core | F | type-1 TG repeat | 1ICF.I |
| 659-726 | Core | G | type-1 TG repeat | 1ICF.I |
| 727-921 | Core | H | type-1 TG repeat | 1ICF.I |
| 922-1008 | Core | I | similar to type-1 (dimer) | de novo |
| 1023-1073 | Core | J | type-1 TG repeat | 1ICF.I |
| 1074-1145 | Core | K | type-1 TG repeat | 1ICF.I |
| 1146-1211 | Core | L | type-1 TG repeat | 1ICF.I |
| 1210-1283 | Flap | M | Fv from an IgM | 1IGM |
| 1284-1438 | Flap | N | Fv from an antibody | 2E27 |
| 1439-1510 | Arm | O | TNF/EGF/laminin-like | 5wiw |
| 1511-1565 | Arm | P | type-1 TG repeat | 1ICF.I |
| 1603-1723 | Arm | Q | type-3 TG repeat | U domain |
| 1724-1892 | Arm | R | type-3 TG repeat | U domain |
| 1893-1995 | Arm | S | type-3 TG repeat | U domain |
| 1996-2129 | Arm | T | type-3 TG repeat | U domain |
| 2130-2186 | Arm | U | type-3 TG repeat | de novo |
| 2187-2728 | CTD | V | ChEL (dimer) | 5HQ3 |