Table 3.
Hazard Ratios for Acute Kidney Injury and Acute Renal Failure With Use of LC-MS vs. Immunoassay for Tacrolimus Monitoringa
| Analysisb | Acute Kidney Injury | Acute Renal Failure |
|---|---|---|
| Unadjusted | HR, 1.78 (1.10–2.87) | HR, 1.53 (0.69–3.41) |
| Adjusted | HR, 1.65 (1.02–2.67) | HR, 1.43 (0.69–3.41) |
| Unadjusted, with death as competing risk | SHR, 1.91 (1.18–3.09) | SHR, 1.73 (0.77–3.92) |
| Adjusted, with death as competing risk | SHR, 1.81 (1.14–2.90) | SHR, 1.63 (0.70–3.82) |
aData are hazard ratio (HR) or subdistribution hazard ratio (SHR) with 95% confidence interval. LC-MS = liquid chromatography–mass spectrometry.
bCompeting risks regression was used to model death as a competing risk. Adjusted models included age, sex, baseline renal function, and race.