Table 3.
Summary of studies on perinatal cases of coronavirus disease 2019
| Variable | Chen et al. [40] | Liu et al. [42] | Zhu et al. [44] |
|---|---|---|---|
| Study area | Wuhan, China | Outside Wuhan, China | Hubei Province, China |
| No. of pregnant women cases (laboratory-confirmed SARS-CoV-2) | 9 | 13 | 9 |
| No. of births | 9 | 10 | 10 |
| Study period | 20 Jan–31 Jan, 2020 | 8 Dec 2019–25 Feb, 2020 | 20 Jan–5 Feb, 2020 |
| Maternal age (yr), median (range) | 28 (26–40) | 30 (22–36) | 30 (25–35) |
| Gestational age (wk), median (range) | 37 wk 2 days (36 wk–39 wk 4 days) | 35 wk (25 wk–38 wk 3 days) | 34 wk 6 days (31–39 wk) |
| Maternal severe pneumonia | 0 (0%) | 1a) (7.7%) | NA |
| Discharge without complication before delivery | 0 (0%) | 3 (23.1%) | 0 (0%) |
| Delivery-related information | |||
| Caesarean section | 9 (100%) | 10 (100%) | 7 (77.8%) |
| Preterm labor/delivery | 4 (44.4%) | 6 (60.0%) | 6 (66.7%) |
| Fetal distress | 2 (22.2%) | 3 (30.0%) | 6 (66.7%) |
| Premature rupture of the membranes | 2 (22.2%) | 1 (10.0%) | 3 (33.3%) |
| Stillbirth | 0 (0%) | 1a) (10.0%) | 0 (0%) |
| Neonatal asphyxia | 0 (0%) | 0 (0%) | 0 (0%) |
| Postnatal death | 0 (0%) | 0 (0%) | 1b) (10.0%) |
NA, not available; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
a)
The mother’s condition deteriorated during hospitalization, requiring mechanical ventilation with extracorporeal membrane oxygenation support.
b)
The neonate died of refractory shock and gastric bleeding.