Fig. 2. Lung histopathology during murine pneumonia infection with Serotype 1 (ST217) and Serotype 2 (D39) S. pneumoniae.

Mice were infected as described in Fig. 1. Lung sections from infected mice were stained with haematoxylin and eosin to show changes in lung pathology during pneumococcal infection with either 1 (ST217S) or 2(D39) at 18 and 24 h post infection (5 mice/group/timepoint). Lung sections from naïve mice (n = 5) are also shown. Scale bars =  200 μm.