Table 2.

HLA-DRB1 alleles distribution in individuals with type 1 diabetes and without T1D.

DRB1*	Individuals without T1D N (%)	Individuals with T1D N (%)	OR	CI	P-value
01	1,012 (9.89%)	151 (7.41%)	0.73	0.61–0.87	0.000
03	1,014 (9.91%)	626 (30.72%)	4.03	3.60–4.51	0.000
04	1,283 (12.54%)	610 (29.93%)	2.98	2.66–3.33	0.000
07	1,321 (12.91%)	139 (6.82%)	0.49	0.41–0.59	0.000
08	644 (6.29%)	67 (3.29%)	0.51	0.39–0.65	0.000
09	163 (1.59%)	77 (3.78%)	2.43	1.84–3.19	0.000
10	202 (1.97%)	24 (1.18%)	0.59	0.39–0.91	0.015
11	1,211 (11.84%)	69 (3.39%)	0.26	0.20–0.33	0.000
12	162 (1.58%)	19 (0.93%)	0.58	0.36–0.94	0.026
13	1,397 (13.65%)	165 (8.10%)	0.56	0.47–0.66	0.000
14	415 (4.06%)	15 (0.74%)	0.17	0.10–0.29	0.000
15	1,027 (10.04%)	44 (2.16%)	0.2	0.15–0.27	0.000
16	381 (3.72%)	32 (1.57%)	0.41	0.28–0.59	0.000

T1D = type 1 diabetes mellitus; n = number of individuals; OR = odds ratio; CI = confidence interval; DRB1*01 included 01:01, 01:02, 01:03 and 01:28; DRB1*03 included 03:01, 03:02, 03:05, 03:07, 03:11, 03:12, 03:15, 03:37, 03:52 and 03:61; DRB1*04 included 04:01, 04:02, 04:03, 04:04, 04:05, 04:06, 04:07, 04:08, 04:09, 04:10, 04:11, 04:14, 04:29 and 04:50; DRB1*07 included 07:01, 07:11 and 07:15; DRB1*08 included 08:01, 08:02, 08:03, 08:04, 08:06, 08:07 and 08:10; DRB1*09 included 09:01 and 09:10; DRB1*10 included 10:01 and 10:03; DRB1*11 included 11:01, 11:02, 11:03, 11:04, 11:06, 11:11, 11:13, 11:18, 11:19, 11:34 and 11:37; DRB1*12 included 12:01, 12:01 G, 12:02, 12:05 and 12:38; DRB1*13 included 13:01, 13:02, 13:03, 13:04, 13:05, 13:11, 13:15, 13:23, 13:31, 13:40, 13:42, 13:49 and 13:56; DRB1*14 included 14:01, 14:02, 14:03, 14:04, 14:06, 14:07, 14:13, 14:17, 14:21, 14:54 and 14:81; DRB1*15 included 15:01, 15:02, 15:03, 15:18 and 15:20; DRB1*16 included 16:01 and 16:02.