Table 3.
HLA-DQB1 alleles distribution in individuals with type 1 diabetes and without T1D.
| DQB1* | T1D Individuals N (%) | Individuals with T1D N (%) | OR | CI | P value |
|---|---|---|---|---|---|
| 02 | 1,969 (19.24%) | 837 (41.07%) | 2.93 | 2.64–3.24 | 0.000 |
| 03 | 2,873 (28.08%) | 715 (35.08%) | 1.38 | 1.25–1.53 | 0.000 |
| 04 | 892 (8.72%) | 64 (3.14%) | 0.34 | 0.26–0.44 | 0.000 |
| 05 | 1,901 (18.58%) | 243 (11.92%) | 0.59 | 0.51–0.68 | 0.000 |
| 06 | 2,597 (25.38%) | 179 (8.78%) | 0.28 | 0.24–0.33 | 0.000 |
T1D = type 1 diabetes mellitus; n = number of individuals; OR = odds ratio; CI = confidence interval, DQB1*02 included 02:01, 02:02, 02:03; DQB1*03 included 03:01 G, 03:02, 03:03, 03:04, 03:05, 03:14, 03:34, 03:40/03:110/03:141/03:155, 03:10/03:139/03:186 and 03:41; DQB1*04included 04:01, 04:02 and 04:04; DQB1*05 included 05:01, 05:02, 05:03, 05:04, 05:05, 05:07, 05:11 and 05:47/05:165; DQB1*06 included 06:01, 06:02, 06:03, 06:04, 06:05, 06:08, 06:09, 06:10, 06:11, 06:19, 06:26 N, 06:27, 06:33, 06:38, 06:49 and 06:72.