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. 2020 Apr 20;10:6625. doi: 10.1038/s41598-020-63465-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Simulated data. Liver weight is reduced in the drug-treated group (p = 0.014; A), as is body weight (p < 0.001; B). There are no differences between groups for relative organ weights (p = 0.710; C), suggesting (incorrectly) that changes in liver weight simply reflect changes in overall body weight. Relationship between liver and body weight shows that for a given body weight, animals in the drug-treated group have higher liver weights than control animals (D).