Table 2.

Basic characteristics of mothers fed a control diet or a folic acid-oversupplemented diet and their offspring.

A) Mothers
	GD (days)	CN		HFA
Body mass (g)	0	18.8 ± 0.9		18.5 ± 0.5
	18	34.8 ± 1.4		33.4 ± 0.6
Food intake /day (g)	0	2.0 ± 1.2		2.2 ± 1.1
	18	3.6 ± 0.4		3.4 ± 0.2
	18	3.6 ± 0.4		3.4 ± 0.2
Number of offspring (n)		6.7 ± 0.4		5.5 ± 0.3*
B) Offspring
	PD (days)	Male	Female	Male	Female
Body mass (g)	8	4.3 ± 0.3	3.8 ± 0.1	3.8 ± 0.1	3.6 ± 0.1
	22	9.0 ± 0.2	9.1 ± 0.3	9.1 ± 0.2	8.9 ± 0.3
	53	22.2 ± 0.6	18.2 ± 0.4	22.3 ± 1.2	17.5 ± 0.3
Food intake (g) (PD22-53days)		86.3 ± 6.3		90.3 ± 4.7

A) Body mass and food intake of C57BL/6J mice fed a CN or an HFA diet at GD 0 and 18. The numbers of offspring born were counted. The number of offspring were less than CN mice by using Student’s t-test (*P < 0.05). B) The mean offspring body mass for each group at PD 8, 22, and 53 and their food intake (PD 22−53) were measured. Values are expressed as mean ± SEM for 10 mice. CN, control; HFA, high-folic acid; GD, gestational day; PD, postnatal day.