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. 2020 Apr 18;54:102733. doi: 10.1016/j.ebiom.2020.102733

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© 2020 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 5 — Kinetics and magnitude of DENV-reactive IgM/IgG/IgA in circulation following primary or secondary DENV infection. (A) Limiting dilution DENV-1 capture ELISA analysis of relative virus-reactive IgG, IgA, IgM levels present in serum obtained from three subjects with serologically- and PCR-confirmed primary DENV-1 infections. (B) Limiting dilution DENV-1 capture ELISA analysis of relative virus-reactive IgG, IgA, IgM levels present in serum obtained from three subjects with serologically- and PCR-confirmed secondary DENV-1 infections. (C) Single-dilution DENV-1 capture ELISA analysis of the relative virus-reactive IgG, IgA, IgM levels present in acute infection serum samples obtained from subjects with serologically and PCR confirmed primary (n = 5) and secondary (n = 4) DENV-1 infections. (D) Single-dilution DENV-1 capture ELISA analysis of the relative virus-reactive IgG, IgA, IgM levels present in early-convalescent serum samples obtained from subjects with serologically and PCR confirmed primary and secondary DENV-1 infections. Error bars indicate +/- SEM. ** p < 0.01, one-way ANOVA.