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. 2020 Apr 20;11:1898. doi: 10.1038/s41467-020-15655-5

Fig. 6. Associations between altered inter-network connectivity strength and posttraumatic stress (PTS) symptom severity.

Fig. 6

Greater functional coupling among the SAN–CEN–DMNa (r = −0.33, P = 0.02) or inter-network connection cluster 1 (r = −0.34, P = 0.02) was associated with lower PTS symptom severity. Reduced negative coupling between the SAN and DMNa (r = −0.32, P = 0.02) or inter-network connection cluster 2 (r = −0.37, P = 0.009) was associated with higher PTS symptom severity. Partial correlation analyses were used to assess the relationships between altered inter-network connectivity strength and PTS symptom severity in the stress-exposed group (n = 52) of data set 2, including age and sex as covariates. Red and blue lines in the schematic diagram for inter-network clusters indicate the positive and negative coupling of networks, respectively. Source data are provided as a Source Data file. CAPS Clinician-Administered Posttraumatic Stress Disorder Scale for DSM-4, DMN default mode network, DMNa default mode network, anterior, SAN salience network, CEN central executive network, SMN sensorimotor network, VIN visual network.