Table 1.

Summary of changes induced by N1 and Cxcl10 within the culture systems. The conditions evaluated and observations are listed; those changed shown in bold. N/a – not applicable, n/d = not done.

	MNLC		MG		MNLC + MG		MNLC + MG (separated)	CXCL10
	24 h	7 d	24 h	7 d	24 h	7d	7d	7d
Metabolism	unchanged	unchanged	unchanged	unchanged	Increased	Increased	unchanged	Increased
MG morphology	n/a	n/a	Non-ramified	Non-ramified	Non-ramified	Ramified	Non-ramified	n/a
MNLC morphology	Less surface area / tightly packed clusters	Less surface area / tightly packed clusters	Less surface area / tightly packed clusters	Less surface area / tightly packed clusters	Less surface area / tightly packed clusters	Increased surface area / less tightly packed clusters	Less surface area / tightly packed clusters	Increased surface area / less tightly packed clusters
MG-MNLC contact	n/a	n/a	n/a	n/a	unchanged	Increased	n/a	n/a
Cxcl10 secretion	unchanged	unchanged	unchanged	unchanged	Increased	n/d	unchanged	n/a
GM1 contact site accumulation	n/a	n/a	n/a	n/a	Increased	n/d	n/a	n/a