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. 2020 Apr 20;11:1881. doi: 10.1038/s41467-020-15749-0

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a RP : rRNA ratio for each RP (abundance of each RP divided by rRNA abundance) was calculated in all growth conditions. The p-values indicated are from two-sided Student’s t-tests. Center line, median; box limits, upper and lower quartiles; whiskers, 1.5× interquartile range. b Model of ribosome complex diversity and abundance. Each complex ribosome contains 54 “core” RP subunits that are highly expressed and samples a subset of 22 RP subunits expressed an order of magnitude lower. c The total number of ribosomes in the cell decreases, whereas diversity of ribosomes varies quadratically, with the number of RP subunits complexed. d Relative abundance of RP subunits in N-limited chemostats compared with C-limited chemostat. RP paralogs were summed and labeled with standard gene name. The 17 RP subunits that were selectively upregulated by >2-fold in N-limited chemostats are indicated with a gray dot.