Table 2.

Patients with PRE tumors available who had heterogeneous tumor responses to PD-1 inhibition.

Patient ID	Patient responsea	Pre-treatment tumor and subsequent response to PD-1 inhibitionb		Patient status
		Lesion core biopsy site	Lesion response
24	PR	Axillary LN	PD	Alive
34	PD	Thigh SC	SD	Dead
35	PD	Thigh SC	CR	Dead
45	PD	Axillary LN	PR	Dead
49	PD	Groin LN	PR	Alive

CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; LN, lymph node; SC, subcutaneous.

^aPatient response was determined using immune-related response criteria

^bPre-treatment tumor was core biopsied and response of this same lesion to PD-1 inhibition was evaluated