TABLE 4.
Log2 fold change (FC) and false discovery rate (FDR) of differentially expressed immune-related genesa
| Gene | FC | FDR |
|---|---|---|
| Cytokines | ||
| Interferon gamma | 6.620001 | 0.0006 |
| Interleukin 8-like 1 (chCXCLi1) | 5.391872 | 0.0002 |
| Interleukin 17A | 4.321906 | 0.0039 |
| Interleukin 22 | 4.285866 | 0.0016 |
| Interleukin 6 | 3.927618 | 0.0017 |
| Interleukin 1, beta | 3.695163 | 0.0006 |
| TNF superfamily member 15 | –3.054895 | 0.0014 |
| Chemokines | ||
| C-X-C motif chemokine ligand 13-like 2 | 7.858709 | 6e-05 |
| C-C motif chemokine ligand 26 | 6.564404 | 0.0001 |
| Gallus gallus C-X-C motif chemokine ligand 13 | 6.448406 | 0.0002 |
| Chemokine (C-C motif) ligand 4 (MIP-1β) | 5.139185 | 0.0008 |
| X-C motif chemokine ligand 1 (lymphotactin) | 4.978717 | 0.0036 |
| C-C motif chemokine ligand 19 (MIP-3β) | 4.245883 | 3e-05 |
| Chemokine ah221 (chCCLi9) | 3.765825 | 0.0087 |
| C-C motif chemokine ligand 20 (MIP-3α) | –3.298172 | 0.0063 |
| C-C motif chemokine ligand 1 (chCCLi5) | 3.265933 | 0.0033 |
| Cytokine receptors | ||
| Interleukin-13 receptor alpha 2 | 5.445273 | 1e-05 |
| Interleukin-2 receptor subunit gamma | 5.263067 | 1e-05 |
| Tumor necrosis factor receptor superfamily member 13B | 5.124457 | 2e-05 |
| Granulocyte colony stimulating factor 3 receptor | 4.648147 | 0.0002 |
| Interleukin-21 receptor | 4.558267 | 0.0008 |
| Interleukin-1 receptor type 1 | –4.154731 | 0.0001 |
| Tumor necrosis factor receptor superfamily member 19 | –3.451626 | 0.0021 |
| Transforming growth factor beta receptor 3 | –3.298024 | 0.0005 |
| Interleukin-1 receptor-like 2 | –3.280008 | 0.0005 |
| Interleukin-20 receptor subunit alpha | 3.216855 | 0.0002 |
| Granulocyte-macrophage colony-stimulating factor receptor alpha like | 3.054296 | 0.0037 |
| Interleukin-1 receptor-associated kinase 1 binding protein 1 | –2.839971 | 0.0004 |
| Tumor necrosis factor receptor superfamily member 6B | 2.696494 | 0.0069 |
| Death domain containing TNF receptor superfamily member 23 | –2.5137 | 0.0088 |
| Tumor necrosis factor receptor superfamily member 1B | 2.435101 | 0.0016 |
| Chemokine receptors | ||
| C-C motif chemokine receptor 10 | 6.595925 | 3e-05 |
| C-C motif chemokine receptor 5 | 5.054953 | 0.0005 |
| C-X-C motif chemokine receptor 1 | 4.604372 | 0.003 |
| C-X3-C motif chemokine receptor 1 | 3.690204 | 0.0003 |
| C-X-C motif chemokine receptor 4 | 2.782461 | 0.0005 |
| Toll-like receptors | ||
| Gallus gallus Toll-like receptor 15 | 3.935744 | 0.0017 |
| Toll-like receptor 5 | –3.279345 | 0.0007 |
| Toll-like receptor 7 | 3.001301 | 0.0028 |
| MHC proteins | ||
| Major histocompatibility complex, class II, DM beta 1 | 5.013108 | 0.0004 |
| Major histocompatibility complex, class II, DM beta 2 | 4.096815 | 1e-05 |
| Gallus gallus major histocompatibility complex class II beta chain BLB2 | 3.429747 | 0.0003 |
| Major histocompatibility complex class II beta chain BLB1 | 3.391866 | 0.0004 |
| Major histocompatibility complex, class II, DM alpha | 3.289581 | 7e-05 |
| Class I histocompatibility antigen, F10 alpha chain-like 3 | 2.932091 | 0.0061 |
| Major histocompatibility complex class I antigen BF2 | 2.464203 | 4e-05 |
| Major histocompatibility complex class I antigen BF2 | 2.464203 | 4e-05 |
| Immunoglobulin and receptor proteins | ||
| Immunoglobulin superfamily member 1-like 7 | 5.210969 | 0.0019 |
| Immunoglobulin lambda-like polypeptide 1 | 4.885844 | 3e-06 |
| Immunoglobulin superfamily member 1-like 2 | 4.413245 | 0.0015 |
| Immunoglobulin superfamily member 1 | 4.030709 | 0.0008 |
| Immunoglobulin like domain containing receptor 1 | –2.810537 | 0.0042 |
| Polymeric immunoglobulin receptor | –2.056498 | 0.0002 |
| Immunoglobulin superfamily member 9 | –1.978692 | 0.0034 |
| V-set and immunoglobulin domain containing 10 | –1.725352 | 0.0093 |
a
An FDR of <0.01 was considered significant.