. 2020 Apr 20;88(5):e00881-19. doi: 10.1128/IAI.00881-19

TABLE 2.

Differentially expressed genes in NM swab samples from CL patients^a

Gene	CLⁿ⁻ patients^b (n = 4)		CLⁿ⁺ patients^b (n = 4)		Fold difference (2^−ΔΔCt CLⁿ⁻ vs CLⁿ⁺)	P value^c
Gene	Avg 2^−ΔCt	SD	Avg 2^−ΔCt	SD	Fold difference (2^−ΔΔCt CLⁿ⁻ vs CLⁿ⁺)	P value^c
ADRB2	0.007	0.002	0.025	0.030	1.95	0.200
ALOX5	0.036	0.061	0.027	0.024	1.52	0.485
BCL6	0.013	0.001	0.022	0.011	1.61	0.057
FCER1A	0.008	0.006	0.027	0.025	3.03	0.342
IFNGR2	0.015	0.007	0.031	0.024	1.78	0.342
IL12A	0.003	0.001	0.012	0.016	2.29	0.342
IL4R	0.008	0.003	0.018	0.005	2.15	0.028
IL5RA	0.004	0.002	0.012	0.006	2.31	0.028
KIT	0.003	0.002	0.011	0.012	2.21	0.200
LTB4R	0.004	0.004	0.019	0.015	4.72	0.114
POSTN	0.001	0.0006	0.022	0.023	7.09	0.028
SATB1	0.005	0.001	0.047	0.069	3.75	0.028
STAT6	0.009	0.004	0.042	0.038	3.37	0.057
TGFB1	0.001	0.002	0.018	0.029	5.79	0.114

CL, cutaneous leishmaniasis; NM, nasal mucosa; SD, standard deviation; CLⁿ⁺, patients with Leishmania-positive NM samples; CLⁿ⁻, patients with Leishmania-negative NM samples. Boldface indicates significantly different gene expression.

Gene expression values (2^−ΔCt) of differentially modulated genes in NM swab samples.

P values were derived from the Mann-Whitney test.