FIG 7.

Vaccination with CspZ triggered antibodies against FH. Sera from five C3H/HeN mice inoculated with CspZ, CspZ-YA, or PBS (negative control) at 42 dpii were incubated with microtiter plate wells coated with human or mouse FH. Mouse IgG antibodies bound to FH were detected using goat anti-mouse IgG. Data shown are the geometric mean ± geometric standard deviation of antibody titers from each group of mice. Significant differences (P < 0.05, Mann-Whitney test) in levels of antibody titers relative to that in sera from PBS-inoculated mice (*) or between two groups relative to each other (#) are indicated.