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. 2020 Apr 20;88(5):e00895-19. doi: 10.1128/IAI.00895-19

TABLE 2.

Spearman’s correlation coefficients for biochemical markers of endothelial activation, parasitemia, clinical score, and platelet countd

Marker Spearman’s correlation coefficient
Parasitemia
Clinical score
OPG
Angiopoetin-2
vWF
Platelet count
P. falciparum P. vivax P. falciparum P. vivax P. falciparum P. vivax P. falciparum P. vivax P. falciparum P. vivax P. falciparum P. vivax
Parasitemia −0.057 0.603a 0.229 0.562c 0.051 0.146 −0.038 0.295b −0.326 −0.574b
Clinical score −0.057 0.603a −0.119 0.818c −0.588a 0.425 −0.109 0.564a −0.156 −0.257
OPG 0.229 0.562c −0.119 0.818c 0.220 0.384c 0.256 0.463c 0.024 −0.472b
Angiopoetin-2 0.051 0.146 −0.588 0.425 0.220 0.384c 0.206 0.324c 0.145 −0.040
vWF −0.038 0.295b −0.109 0.564a 0.256 0.463c 0.206 0.324c −0.384a −0.057
Platelet count −0.326 −0.574b −0.156 −0.257 0.024 −0.472b 0.145 −0.040 −0.384 −0.057
a

P < 0.05.

b

P < 0.01.

c

P < 0.001.

d

Parasitemia is in log10 number of parasites per milliliter, the clinical score is the cumulative clinical score, OPG is the osteoprotegerin concentration (in picograms per milliliter), angiopoetin-2 is the angiopoetin-2 concentration (in picograms per milliliter), vWF is the von Willebrand factor concentration (in milliunits per milliliter), the platelet count is in 109 cells per liter, P. falciparum represents the P. falciparum-inoculated group, and P. vivax represents the P. vivax-inoculated group. P values represent the P values of the correlation.