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. 2019 Jul 28;22(5):734–739. doi: 10.1093/ntr/ntz129

Table 2.

Mean Change in Withdrawal and Control Symptoms With Abstinence

Vaping Abstinent Increase t value
Mean Mean Mean
Withdrawal (0–3)
 Mean 0.16 0.57 0.41 6.5***
 Angry, irritable 0.21 0.88 0.67 6.1***
 Anxious, nervous 0.14 0.59 0.45 4.1***
 Increased appetite 0.13 0.62 0.49 5.1***
 Difficulty concentrating 0.10 0.52 0.41 4.6***
 Depressed, sad 0.08 0.28 0.21 3.6***
 Insomnia 0.26 0.38 0.12 2.1*
 Restlessness 0.17 0.71 0.53 5.1***
Craving (0–5)
 E-Cig craving
  How much of time urge 1.97 2.47 0.49 3.7***
  How strong urge 1.94 2.62 0.68 4.9***
 Tobacco cigarette craving
  How much of time urge 0.11 0.40 0.28 2.7*
  How strong urge 0.08 0.38 0.30 2.9**
Potential withdrawal items (0–3)
 Impatient, impulsive 0.10 0.57 0.47 4.5***
 Less enjoy pleasant events 0.03 0.31 0.28 3.1**
 Less positive outlook 0.04 0.27 0.22 2.7**
 Mood swings 0.05 0.41 0.36 3.9***
Control items (0–3)
 Diarrhea 0.04 0.07 0.03 0.6
 Headache 0.19 0.33 0.14 1.9
 Tremors 0.00 0.15 0.15 3.4**

*p < .05, **p < .01, ***p < .001.