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. 2019 Apr 10;22(5):747–755. doi: 10.1093/ntr/ntz035

Table 2.

Awareness of Chemicals in Cigarette Smoke Among Adolescents

Chemical Wave 1
2014–2015 (%)
Wave 2
2016–2017 (%)
Difference (95% CI) p
1,3-Butadiene 7.8 12.3 4.5 (−3.4 to 12.4) .263
1-Aminoaphthalene 13.6 11.4 −2.1 (−101 to 5.9) .601
2-Aminonaphthalene 13.2 9.6 −3.6 (11.1 to 3.9) .347
4-Aminobiphenyl 13.0 4.8 −8.2 (−14.1 to −2.4) .005
Acetaldehyde 18.1 17.1 −1.1 (−11.2 to 9.0) .837
Acrolein 5.9 7.9 2.0 (−4.0 to 7.9) .519
Acrylonitrile 13.6 13.9 0.3 (−8.5 to 9.1) .950
Ammonia 47.4 36.0 −11.4 (−23.4 to 0.6) .062
Arsenic 41.9 29.0 −12.9 (−25.0 to −0.8) .036
Benzene 37.2 24.4 −12.8 (-24.4 to −1.1) .032
Benzo-a-pyrene 15.3 11.7 −3.6 (−12.8 to 5.7) .450
Carbon monoxide 58.8 45.0 −13.8 (−27.5 to −0.0) .049
Crotonaldehyde 19.8 19.6 −0.3 (−10.0 to 9.5) .957
Formaldehyde 41.4 33.3 −8.1 (−20.7 to 4.4) .203
Hydrogen cyanide 32.9 25.5 −7.4 (−18.6 to 3.8) .192
Isoprene 18.0 13.7 −4.3 (−14.0 to 5.3) .378
Lead 33.5 32.4 −1.0 (−12.9 to 10.9) .866
Naphthalene 20.0 7.3 −12.6 (−20.8 to −4.5) .003
Nicotine 92.4 90.3 −2.1 (−9.6 to 5.5) .587
Nitrosamine 20.8 11.7 −9.1 (−17.2 to −1.0) .028
N-nitrosonornicotine 61.8 55.6 −6.2 (−20.0 to 7.6) .376
NNK 12.7 11.9 −0.8 (−9.8 to 8.3) .866
Toluene 11.1 9.0 −2.1 (−10.0 to 5.9) .605
Uranium 19.4 6.2 −13.2 (−21.2 to −5.2) .001
Overall 27.9 21.7 −6.2 (−8.4 to −4.0) <.001

2014–2015 n = 1125; 2016–2017 n = 975. The ns for each chemical differ slightly but are comparable. Percentages are weighted. NNK = nicotine-derived nitrosamine ketone. The threshold value of statistical significance is p = .05.