Table 3.
Univariate and multivariate Cox's proportional hazard regression model analyses of factors predicting DFS
| Items | Univariate Cox's regression | Multivariate Cox's regression | ||
|---|---|---|---|---|
| P value | HR (95%CI) | P value | HR (95%CI) | |
| KIF2A high expression | <.001 | 1.725 (1.368‐2.173) | <.001 | 1.587 (1.233‐2.042) |
| Age (>60 y) | .124 | 1.196 (0.952‐1.503) | .431 | 1.100 (0.868‐1.393) |
| Male | .638 | 1.069 (0.811‐1.409) | .325 | 0.857 (0.630‐1.165) |
| Smoke | .289 | 1.132 (0.901‐1.422) | .352 | 1.122 (0.880‐1.432) |
| Drink | .173 | 1.176 (0.932‐1.483) | .067 | 1.247 (0.985‐1.579) |
| Higher pathological grade | <.001 | 1.537 (1.281‐1.845) | .003 | 1.355 (1.110‐1.654) |
| Tumor size (>5 cm) | <.001 | 1.595 (1.269‐2.005) | .228 | 0.819 (0.592‐1.133) |
| LYN metastasis | <.001 | 2.675 (2.109‐3.393) | <.001 | 2.401 (1.779‐3.242) |
| Higher TNM stage | <.001 | 1.537 (1.331‐1.776) | .132 | 1.178 (0.952‐1.457) |
| CEA (>5 ng/mL) | .018 | 1.322 (1.049‐1.668) | .024 | 1.316 (1.037‐1.671) |
Abbreviations: CEA, carcinoembryonic antigen; CI, confidence; DFS, disease‐free survival; HR, hazard ratio; KIF2A, kinesin superfamily protein 2A; LYN, lymph node.