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. 2019 Dec 27;34(4):e23146. doi: 10.1002/jcla.23146

Table 3.

Stratification analysis of risk genotypes with endometrial cancer susceptibility

Variables

rs591291

(cases/controls)

AOR (95% CI)a P a

rs664589

(cases/controls)

AOR (95% CI)a P a

rs4102217

(cases/controls)

AOR (95% CI) a P a
AA AG/GG CG/CC GG AA/AC CC
Surgery history
Yes 45/77 8/17 0.81 (0.32‐2.02) .644 50/92 3/2 2.76 (0.45‐17.06) .275 52/92 1/2 0.89 (0.08‐9.99) .921
No 168/301 28/49 1.02 (0.62‐1.69) .927 190/350 6/2 5.53 (1.11‐27.64) .037 192/345 4/6 1.20 (0.33‐4.30) .782
Menopause
Yes 141/228 24/37 1.05 (0.60‐1.83) .866 158/2657 7/0 164/258 1/6 0.26 (0.03‐2.20) .217
No 72/150 12/29 0.86 (0.42‐1.79) .690 82/177 2/4 1.08 (0.19‐6.02) .929 80/179 4/2 4.48 (0.80‐24.93) .087
Delivery
=0 5/4 1/0 6/4 0/0 6/4 0/0
=1 57/5 85/13 0.57 (0.19‐1.70) .315 60/97 2/1 3.23 (0.29‐36.43) .342 62/97 0/1
≥2 151/289 30/53 1.08 (0.66‐1.77) .748 174/341 7/3 4.57 (1.17‐17.90) .029 176/336 5/7 1.36 (0.43‐4.36) .601
BMI
<18.5 18/26 3/1 4.33 (40.42‐45.06) .220 21/27 0/0 21/27 0/0
18.5 ≤ BMI ≤ 24.9 96/204 17/43 0.84 (0.46‐1.55) .677 111/246 2/2 2.22 (0.31‐15.93) .429 112/241 1/6 0.36 (0.04‐3.01) .345
25.0 ≤ BMI ≤ 29.9 76/123 13/19 1.11 (0.52‐2.37) .793 83/141 6/2 5.10 (1.01‐25.83) .049 86/141 3/2 2.46 (0.40‐15.01) .330
30.0 ≤ BMI ≤ 40 19/16 3/3 0.84 (0.15‐4.76) .846 21/19 1/0     21/19 1/0
FIGO stage
I 190/378 23/378 0.90 (0.56‐1.45) .675 211/422 8/4 4.00 (1.18‐13.61) .027 214/437 5/8 1.40 (0.45‐4.35) .566
II 29/66 7/66 1.82 (0.72‐4.57) .203 29/422 1/4 15.4 (1.06‐224.76) .046 30/437 0/8

Abbreviations: AOR, adjusted odds ratio; CI, confidence interval.

a

Adjusted for surgery history, menopause, delivery, and BMI.

The results were in bold, if the 95% CI excluded 1 or P < .05.