Table 4.
The frequency of inferred haplotypes of MALAT1 based on observed genotypes and their association with the risk of endometrial cancer
| rs591291 | rs664589 | rs4102217 | Cases (N = 555) | Controls (N = 535) | Crude OR (95% CI) | P | Adjusted OR (95% CI) | P a |
|---|---|---|---|---|---|---|---|---|
| C | C | G | 244 (49.0%) | 442 (49.9%) | 1.00 | 1.00 | ||
| T | C | G | 132 (26.5%) | 240 (27.1%) | 1.00 (0.77‐1.30) | .978 | 0.99 (0.76‐1.30) | .948 |
| C | G | G | 10 (2.0%) | 6 (0.7%) | 3.02 (1.08‐8.41) | .035 | 2.80 (1.00‐7.86) | .050 |
| C | G | C | 0 (0.0%) | 0 (0.0%) | – | – | – | – |
| T | G | G | 34 (6.8%) | 74 (8.4%) | 0.83 (0.54‐1.29) | .408 | 0.79 (0.50‐1.24) | .300 |
| T | G | C | 0 (0.0%) | 1 (0.1%) | – | – | – | – |
| C | C | C | 49 (9.8%) | 81 (9.1%) | 1.10 (0.74‐1.62) | .644 | 1.03 (0.70‐1.53) | .874 |
| T | C | C | 29 (5.8%) | 42 (2.7%) | 1.25 (0.76‐2.06) | .379 | 1.28 (0.78‐2.13) | .332 |
Abbreviations: CI, confidence interval; OR, odds ratio.
a
Adjusted for surgery history, menopause, delivery, and BMI.
The results were in bold, if the 95% CI excluded 1 or P < .05.