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. 2020 Mar 3;24(7):4092–4104. doi: 10.1111/jcmm.15063

Figure 7.

Figure 7

M6A/STED7/KLF4 axis is established in regulating BCa progression. In BCa, m6A modification is assembled on mRNA by METTL3 with other accessory catalytic subunits and eliminated by FTO and ALKBH5. YTHDF2 specifically recognizes m6A‐mRNA and induces the degradation of target mRNAs, promoting tumorigenesis eventually