Functional annotation and network analyses for blue module. (A) GO enrichment analysis results of blue module are shown. The GO terms are divided into three groups: BP, CC and MF. (B) Network depiction of blue module. Nodes correspond to genes, and lines correspond to connections, with the top 250 connections in blue module shown. (C) GSEA results show that several gene sets enriched in GBMs with high expression levels of CD53. (D) mRNA expression levels of C1QB and FCER1G among molecular subtypes in TCGA and http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE4271 data sets. (E) mRNA expression levels of C1QB and FCER1G among different glioma grades in TCGA, Rembrandt and http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE16011 data sets. Means ± SEM; one‐way ANOVA with Tukey's post hoc test; ns, P > .05, *, P < .05; **, P < .01, ***, P < .001, ****, P < .0001