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. 2020 Feb 19;24(7):4127–4135. doi: 10.1111/jcmm.15069

Figure 6.

Figure 6

Circ_PUM1 promotes the development of endometrial cancer by regulating NOTCH3 proteins via sponges miR‐136.Overexpression of circ_PUM1 increased the expression of NOTCH3, and vice versa (A). High expression of miR‐136 in Ishikawa cells overexpressing circ_PUM1 resulted in a decrease in NOTCH3 expression (B); In nude mouse tumour tissue, low expression of irc_PUM1 inhibited levels of NOTCH3 (C). The results are representative of three separate experiments