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PARP1 genotype and gene expression association. (A) Microarray‐based expression profiling on 17 neuroblastoma cell lines shows a significant association between PARP1 expression and rs907187. (B) SNP‐expression correlation on Genotype‐Tissue Expression (GTEx) through the GTEx portal of Nerve Tibia Tissues. (C) The G allele of rs907187 down‐regulates promoter activity. Transcriptional activity of the pGL3‐PARP1‐CC (CC) and pGL3‐PARP1‐GG (GG) constructs in SKNBE2 neuroblastoma cells
