Figure 3.

A, Effect of hyperlipidemia on inhibition of splenic DCs maturation by lisinopril in mice. CD80, CD86 and CD83 expression as maturation marker was assessed by flow cytometry. B, C, D, qPCR detection of hyperlipidemia affecting the expression of DCs cytokines and chemokines in spleen of mice. E, F, Expression of secretion of Ang II and inflammatory cytokines in the peripheral circulation under hyperlipidemic conditions by ELISA. *P < .05 vs Sham; &P < .05 vs Saline MI; #P < .05 vs WT ACEI + MI