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. 2020 Mar 6;24(7):3948–3957. doi: 10.1111/jcmm.14997

Table 1.

Clinical characteristics of AIH patients and Healthy controls

Parameters AIH HC
NO 32 20
Age (years) 48 (37‐76) 51 (41‐74)
Gender: female/male 24/8 14/6
ALT (U/L) 125.9 ± 108.3* 27.2 ± 8.2
AST (U/L) 101.1 ± 53.7* 22.7 ± 5.7
γ‐GT (U/L) 89.1 ± 30.3* 25.1 ± 7.4
ALP (U/L) 133.4 ± 37.1* 89.5 ± 23.6
Bilirubin (umol/L) 12.5 ± 8.1* 10.8 ± 6.8
Albumin (g/L) 23.8 ± 5.7 25.3 ± 4.8
PT‐INR 1.0 ± 0.9 1.1 ± 0.6
Anti‐ANA (+) 23/32 (71.8%)* 0/20 (0%)
Anti‐ANA titre 1:640 (1:80‐1:10 000)
Anti‐SMA (+) 2/32 (6.25%) 0/20 (0%)
Anti‐SMA titre 1:1000 (1:160‐1:3200)
IgG (g/L) 15.9 ± 3.7* 7.8 ± 2.3
IgM (g/L) 6.9 ± 1.9* 2.64 ± 0.87
IgA (g/L) 4.07 ± 2.3* 1.6 ± 1.1
WBC (*10 9/L) 7.93 (5.6‐11.2)* 5.08 (3.9‐9.2)

Data shown are real case number or mean ± SD.

Normal values: ALP, alkaline phosphatase: 45‐125 μ/L; albumin: 35‐53 g/L; ANA, anti‐nuclear antibody: <1:80; SMA, anti‐mitochondrial antibodies: <1:80; HC, healthy control; AIH, autoimmune hepatitis; ALT, alanine aminotransferase: 5‐40 U/L; AST, aspartate transaminase: 5‐40 U/L; γ‐GT, gamma‐glutamyl transferase: 10‐60 μ/L; IgA:0.4‐2.3 g/L; bilirubin: 3.4‐20.5 umol/L; IgM: 0.7‐4.6 g/L; IgG: 7‐16 g/L.

*

P < .05 vs HC.