Figure 7.
Functionalized gadofullerenes developed for the detection of breast cancer. (A) Scheme of the functionalized gadofullerenes ZD2‐Gd3N@C80 and their tumour targeting capability. The MCF‐7 and MDA‐MB‐231 cells lines were used to obtain low‐risk and high‐risk breast cancer xenografts, respectively. (B) The functionalized gadofullerenes afforded a specific MRI detection of high‐risk breast cancer xenografts. Tumour locations are indicated with white arrow heads. Reprinted with permission from reference,25 copyright 2017 Nature Publishing Group (http://creativecommons.org/licenses/by/4.0/)