Figure 8.

Gadofullerenes developed for multimodal imaging detection of brain tumours. (A, D) T1‐weighted images with gadodiamide contrast. (B, E) T1‐weighted images in which the bright contrast at the infusion site results from ¹²⁴I‐f‐Gd₃N@C₈₀. (C, F) T2‐weighted images with dark contrast due to ¹²⁴I‐f‐Gd₃N@C₈₀. (G) Coronal, (H) axial and (I) sagittal microPET images following ¹⁸F‐FDG injection and the additive image signal that allows for localization of ¹²⁴I‐f‐Gd₃N@C₈₀ within the right hemisphere of the rat brain (arrows indicate infusion sites). (J‐L) MicroPET images display the signal from ¹²⁴I‐f‐Gd₃N@C₈₀. Reprinted with permission from,62 copyright 2012 MDPI (http://creativecommons.org/licenses/by/4.0/)