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. 2017 Feb 17:2–43.e19. doi: 10.1016/B978-0-323-35775-3.00001-1

Figure 1-7.

Figure 1-7

Postulated Sequence of Events in Reversible and Irreversible Ischemic Cell Injury.

Although reduced oxidative phosphorylation and adenosine triphosphate (ATP) concentration have a central role, ischemia can damage membranes directly. ER, Endoplasmic reticulum.

(Courtesy Dr. M.A. Miller, College of Veterinary Medicine, Purdue University; and Dr. J.F. Zachary, College of Veterinary Medicine, University of Illinois.)