Figure 1-7.
Postulated Sequence of Events in Reversible and Irreversible Ischemic Cell Injury.
Although reduced oxidative phosphorylation and adenosine triphosphate (ATP) concentration have a central role, ischemia can damage membranes directly. ER, Endoplasmic reticulum.
(Courtesy Dr. M.A. Miller, College of Veterinary Medicine, Purdue University; and Dr. J.F. Zachary, College of Veterinary Medicine, University of Illinois.)