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. 2017 Feb 17:2–43.e19. doi: 10.1016/B978-0-323-35775-3.00001-1

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Copyright © 2017 Elsevier Inc. All rights reserved.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Figure 1-23 — Apoptosis, Cytologic Features.

A, Pancreas, rat. Individual acinar cells are shrunken, condensed, and fragmented (arrows). Apoptotic bodies are in adjacent cells, but inflammation is absent. H&E stain. B, Hippocampus, brain, mouse. Individual neurons are shrunken, condensed, and fragmented (arrows). H&E stain.

(A courtesy Dr. M.A. Wallig, College of Veterinary Medicine, University of Illinois. B courtesy Drs. V.E. Valli and J.F. Zachary, College of Veterinary Medicine, University of Illinois.)