Table 2.
Main factors associated with the poor prognosis of CUP
| Factor | Explanation |
|---|---|
| Gender | Male more than female |
| Type of metastasis | Multiple brain metastases |
| Organ involvement* | Pleural/lung, Liver, and adrenal involvement |
| Histological type | Adenocarcinoma |
*Conversely, involvement of the lymph node and neuroendocrine histology is correlated with a better survival