Table 6.
Commercially available molecular assays using gene-expression profiling for cancer of unknown primary site
| Supplier | Test | Platform | Material | No. of genes profiled | No. of tumour classes | Reference |
|---|---|---|---|---|---|---|
| Pathwork Diagnostics | ResponseDX Tissue of Origin™ Test | RNA extraction/ microarray | Fresh | 2000 | 10 | 100 |
| BioTheranostics | CancerTYPE ID® | RT-PCR | FFPE | 92 | 54 | 30 |
| Rosetta Genomics-Prometheus | miRview_ mets (ProOnc Tumour SourceDxT) |
RT-PCR for microRNA |
FFPE | 48 | 42 | 101 |
RT-PCR; Reverse transcription polymerase chain reaction. FFPR; Formalin-fixed, Paraffin-embedded.