Table 7.

Alterations of tyrosine kinase in different CUP studies

Marker	c-Myc	Ras	HER-2	EGFR	C-KIT
IHC finding	Expression 96% Overexpression 23%	Expression 92% Overexpression 23%	Expression 65-68% Overexpression 4-27%	Expression 74-75% Overexpression 4-61%	Expression 12-81% Overexpression 4-13%
Reference	102	102	41, 42, 102	41-43	42, 103