Table 9.
Therapeutic options for cancer of unknown primary site according to the European Society of Medical Oncology 80, 104.
| Tumour type of CUP | Treatment plan |
|---|---|
| Poorly differentiated neuroendocrine carcinoma | Platinum + etoposide combination chemotherapy |
| Isolated axillary nodal metastases | Axillary nodal dissection, mastectomy or breast irradiation and adjuvant chemohormonotherapy |
| Adenocarcinoma with a colon profile | Chemotherapy regimens for colorectal cancer |
| Single metastatic deposit from an unknown primary | Resection and/or RT ± systemic therapy |
| Unfavourable subsets | Platinum-based empirical chemotherapy |
RT; radio therapy.