Table 1.
The associations of HMGB1 expression with clinicopathological characteristics in ICGC-LIRI-JP (n=203) cohort
| Feature | Low expression of HMGB1 (n=150) | High expression of HMGB1 (n=53) |
|---|---|---|
| Age(years) | ||
| ≥50 | 139 | 47 |
| <50 | 11 | 6 |
| Gender | ||
| Male | 109 | 44 |
| Female | 41 | 9 |
| Virus | ||
| HBV | 35 | 18 |
| HCV | 88 | 29 |
| HBV and HCV | 2 | 2 |
| Negative | 25 | 4 |
| TNM stage | ||
| I+II | 101 | 28 |
| III+IV | 49 | 25 |
| Portal vein invasion | ||
| Positive | 35 | 14 |
| Negative | 115 | 39 |
| Vein invasion | ||
| Positive | 25 | 12 |
| Negative | 125 | 41 |
| Bile duct invasion | ||
| Positive | 9 | 4 |
| Negative | 141 | 49 |
| Fibrosis | ||
| Yes | 142 | 52 |
| No | 8 | 1 |
| Alcohol | ||
| Yes | 58 | 32 |
| No | 84 | 20 |
| NA | 8 | 1 |
| Smoking | ||
| Yes | 78 | 36 |
| No | 65 | 16 |
| NA | 7 | 1 |
Abbreviations: NA, not available.