Table 1.
Relation between integrin αvβ8 expression and clinicopathologic variables in colon cancer cases
Clinicopathological factors | n (165) |
Αvβ8 expression | P Value |
|
---|---|---|---|---|
Positive (n=61) | Negative (n=104) | |||
Gender | 0.227 | |||
Male | 90 | 37 | 53 | |
Female | 75 | 24 | 51 | |
Age(years) | 0.072 | |||
≤60 | 85 | 37 | 48 | |
>60 | 80 | 24 | 56 | |
Tumor anatomical location | 0.787 | |||
Right hemicolon cancer | 87 | 33 | 54 | |
Left hemicolon cancer | 78 | 28 | 50 | |
T stage | 0.086 | |||
T1# | 4 | 1 | 3 | |
T2# | 19 | 5 | 14 | |
T3# | 66 | 19 | 47 | |
T4# | 76 | 36 | 40 | |
N stage | 0.007 | |||
N0 | 93 | 26 | 67 | |
N1 | 43 | 24 | 19 | |
N2 | 29 | 11 | 18 | |
M stage | 0.029 | |||
M0 | 124 | 40 | 84 | |
M1 | 41 | 21 | 20 | |
TNM stage | 0.018 | |||
I - II | 82 | 23 | 59 | |
III-IV | 83 | 38 | 45 | |
Differentiation | <0.001 | |||
Well | 67 | 19 | 48 | |
Moderate | 59 | 10 | 49 | |
Poor/undifferentiated | 39 | 32 | 7 | |
CD8+TILs density | <0.001 | |||
Low | 73 | 38 | 35 | |
high | 92 | 23 | 69 | |
Survival (60-month follow-up) | 0.003 | |||
Death | 78 | 38 | 40 | |
Censored | 87 | 23 | 64 |
*Log-rank test