Table 2.

Univariate and multivariate analysis of association of clinicopathologic features with 5-year survival in colon cancer

Variable	Univariate analysis				Multivariate analysis
	Relative risk	95% CI	P Value		Relative risk	95% CI	P Value
Age at diagnosis	1.063	1.037, 1.068	0.026		1.085	1.042, 1.082	0.007
Gender
Male	1.000(Ref.)
Female	0.847	0.487, 1.212	0.535
Tumor anatomical location
Right hemicolon cancer	1.000(Ref.)
Left hemicolon cancer	0.653	0.515, 1.164	0.361
T stage
T1	0.021	0.000, > 105	0.892
T2	0.561	0.756, 3.251	0.294
T3	0.975	0.597, 1.579	0.977
T4	1.000(Ref.)
N stage
N0	1.000(Ref.)
N1	1.218	0.627, 2.420	0.534
N2	1.527	0.875, 3.087	0.135
M stage
M0	1.000(Ref.)				1.000(Ref.)
M1	1.531	0.912, 3.142	0.029		1.854	0.967, 3.238	0.037
TNM stage
I	1.000(Ref.)
II	0.573	0.256, 1.387	0.235
III	0.674	0.295, 1.765	0.474
IV	1.264	0.445, 2.789	0.847
Differentiation
Well	1.000(Ref.)				1.000(Ref.)
Moderate	0.901	0.567, 1.723	0.723		1.327	0.573, 1.658	0.256
poor/undifferentiated	2.362	1.406, 4.621	0.002		1.653	0.785, 2.973	0.056
αvβ8
Negative	1.000(Ref.)				1.000(Ref.)
Positive	2.224	1.280, 3.675	<0.001		1.681	0.976, 3.109	0.031