Table 2.
Univariate cox regression was used to reveal the prognostic significance of age related genes in glioma patients.
| TCGA | GSE43378 | |||||||
|---|---|---|---|---|---|---|---|---|
| symbol | Coefficient | HR | P-value | 95% CI | Coefficient | HR | P-value | 95% CI |
| IGFBP2 | 0.44 | 1.55 | <2e-16 | 1.43-1.68 | 0.37 | 1.44 | 3.38e-06 | 1.24-1.68 |
| HOXA5 | 0.34 | 1.35 | <2e-16 | 1.27-1.44 | 0.25 | 1.28 | 0.0013 | 1.1-1.49 |
| SERPINA5 | 0.25 | 1.28 | <2e-16 | 1.21-1.36 | 0.365 | 1.43 | 4.50e-05 | 1.2-1.7 |
| RARRES2 | 0.23 | 1.26 | 1.2E-09 | 1.17-1.36 | 0.24 | 1.27 | 0.0012 | 1-1.46 |
| TIMP1 | 0.37 | 1.44 | <2e-16 | 1.33-1.57 | 0.42 | 1.52 | 1.07e-06 | 1.28-1.79 |
| PLA2G2A | 0.2 | 1.22 | 5.3e-11 | 1.15-1.29 | 0.31 | 1.37 | 4.30e-05 | 1.18-1.59 |
| CYP11A1 | 0.16 | 1.17 | 0.00455 | 1.05-1.30 | -0.03 | 0.97 | 0.79 | 0.81-1.18 |
| MEOX2 | 0.29 | 1.3 | <2e-16 | 1.25-1.41 | 0.26 | 1.29 | 0.0031 | 1.1-1.53 |
| HOXC9 | 0.39 | 1.46 | <2e-16 | 1.35-1.58 | 0.18 | 1.19 | 0.01 | 1.04-1.37 |
| HOXC6 | 0.31 | 1.36 | <2e-16 | 1.27-1.46 | 0.17 | 1.18 | 0.0097 | 1.04-1.34 |
| CXCL14 | 0.1 | 1.11 | 0.0177 | 1.02-1.2 | 0.21 | 1.24 | 0.022 | 1.03-1.48 |
| NR2E1 | 0.35 | 1.42 | 8.8e-01 | 1.27-1.6 | 0.15 | 1.17 | 0.13 | 0.96-1.42 |
| LSP1 | 0.45 | 1.57 | 2.1e-13 | 1.39-1.77 | 0.47 | 1.59 | 0.0031 | 1.17-2.16 |
| SERPINA3 | 0.29 | 1.33 | 2.7e-13 | 1.23-1.44 | 0.25 | 1.28 | 0.00031 | 1.12-1.46 |
| NNMT | 0.3 | 1.34 | 7.2e-16 | 1.25-1.44 | 0.25 | 1.29 | 1.04e-05 | 1.15-1.44 |
| LTF | 0.16 | 1.16 | 1.8e-10 | 1.11-1.22 | 0.14 | 1.15 | 0.000185 | 1.07-1.24 |
| GPX8 | 0.43 | 1.53 | <2e-16 | 1.39-1.68 | 0.41 | 1.5 | 2.90e-06 | 1.27-1.78 |
| EMP3 | 0.45 | 1.56 | <2e-16 | 1.44-1.7 | 0.37 | 1.44 | 4.19e-05 | 1.21-1.72 |
| SERPINE1 | 0.29 | 1.33 | 1.9e-11 | 1.23-1.45 | 0.37 | 1.45 | 7.70e-06 | 1.23-1.7 |
| METTL7B | 0.49 | 1.5 | <2e-16 | 1.38-1.64 | 0.44 | 1.55 | 4.39e-07 | 1.3-1.84 |
| CHI3L2 | 0.26 | 1.29 | 1.9e-10 | 1.19-1.39 | 0.27 | 1.3 | 0.00064 | 1.12-1.52 |
| CHI3L1 | 0.27 | 1.31 | <2e-16 | 1.24-1.38 | 0.27 | 1.31 | 2.81e-05 | 1.15-1.48 |
| TSTD1 | 0.35 | 1.42 | 1.7E-12 | 1.29-1.57 | 0.15 | 1.16 | 0.12 | 0.96-1.4 |
| IGFBPL1 | -0.13 | 0.88 | 0.0039 | 0.81-0.96 | -0.19 | 0.82. | 0.082 | 0.66-1.02 |
| MGAT4C | -0.31 | 0.73 | 1.2e-11 | 0.67-0.8 | -0.35 | 0.71 | 0.0001 | 0.59-0.84 |
| MSTN | -0.03 | 0.97 | 0.397 | 0.9-1.04 | -0.26 | 0.77 | 0.0033 | 0.65-0.92 |
| SFRP2 | -0.25 | 0.78 | <2e-16 | 0.73-0.82 | -0.13 | 0.88 | 0.031 | 0.78-0.99 |
| CLEC4F | -0.31 | 0.74 | 2.8e-08 | 0.66-0.82 | -0.13 | 0.88 | 0.19 | 0.72-1.1 |
| PRLHR | -0.23 | 0.79 | 6.2e-14 | 0.74-0.84 | -0.24 | 0.78 | 0.0011 | 0.68-0.91 |
| IRX1 | -0.04 | 0.96 | 0.26 | 0.9-1.03 | -0.02 | 0.98 | 0.82 | 0.84-1.15 |
| KLRC3 | -0.26 | 0.77 | 1.8e-13 | 0.72-0.83 | -0.18 | 0.83 | 0.017 | 0.71-0.97 |
| LUZP2 | -0.32 | 0.73 | <2e-16 | 0.67-0.78 | -0.35 | 0.71 | 0.0003 | 0.58-0.85 |