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. 2020 Apr 6;11(13):3903–3909. doi: 10.7150/jca.43326

Table 1.

Clinical and imaging characteristics of benign and malignant breast lesions

Benign, n (%) Malignant, n (%) Total P
Age 44.5±9.4 49.3±10.6 0.001
Age <0.001
<50 55(39.0) 86(61.0) 141
≥50 18(17.8) 83(82.2) 101
First-degree relatives with breast cancer 0.70
0 73(30.3) 168(69.7) 241
1 0(0.0) 1(100.0) 1
Tumor size (cm) <0.001
<2 68(57.1) 51(42.9) 119
≥2 15(12.2) 108(87.8) 123
Tumor shape 0.012
Round, oval 73(31.7) 157(68.3) 230
Irregular 0(0.0) 12(100.0) 12
Growth orientation <0.001
Parallel 68(37.0) 116(63.0) 184
Nonparallel 5(8.6) 53(91.4) 58
Margin <0.001
Circumscribed 22(12.0) 162(88.0) 184
Indistinct 51(87.9) 7(12.1) 58
Contour <0.001
Smooth, lobulated 66(45.8) 78(54.2) 144
Angular 7(7.1) 91(92.9) 98
Acoustic shadowing 0.51
Yes 11(28.9) 27(71.1) 38
NO 62(30.4) 142(69.6) 204
Microcalcification <0.001
Yes 11(28.9) 27(71.1) 38
NO 62(30.4) 142(69.6) 204
Echogenicity 0.15
Hypo-echoic 63(28.9) 155(71.1) 218
Complex 10(41.7) 14(58.3) 24
Presence of architectural distortion <0.001
Yes 0(0.0) 33(100.0) 33
No 73(34.9) 136(65.1) 209
Presence of duct ectasia 0.46
Yes 5(26.3) 14(73.7) 19
No 68(30.5) 155(69.5) 223
CDFI level <0.001
0-1 54(57.4) 40(42.6) 94
2-3 19(12.8) 129(87.2) 148
ES score <0.001
1 5(71.4) 2(28.6) 7
2 22(75.9) 7(24.1) 29
3 36(48.6) 38(51.4) 74
4 10(11.2) 79(88.8) 89
5 0(0.0) 43(100.0) 43
ES score <0.001
1-3 63(57.3) 47(42.7) 110
4-5 10(7.6) 122(92.4) 132
US BI-RADS category <0.001
2 1(100.0) 0(0.0) 1
3 26(96.3) 1(3.7) 27
4a 39(83.0) 8(17.0) 47
4b 5(16.1) 26(83.9) 31
4c 2(2.6) 76(97.4) 78
5 0(0.0) 58(100.0) 58
US BI-RADS category <0.001
3-4b 66(88.0) 9(12.0) 75
4b-5 7(4.2) 160(95.8) 167
MRI BI-RADS category <0.001
1 4(80.0) 1(20.0) 5
2 8(100.0) 0(0.0) 8
3 30(93.8) 2(6.3) 32
4 31(20.8) 118(79.2) 149
5 0(0.0) 48(100.0) 48
MRI BI-RADS category <0.001
0-3 42(93.3) 3(6.7) 45
4-5 31(15.7) 166(84.3) 197

Abbreviations: BI-RADS: Breast Imaging-Reporting and Data System; US: ultrasound; MRI: magnetic resonance imaging; ES: elastography; CDFI: color doppler flow imaging