Table 5.
Liver and renal function indices at baseline and end of intervention and percentages of change from baseline1.
| Variable | Baseline | End point | % of Δ |
|---|---|---|---|
| AST, U/L | 16.5 (16.2, 19.8) | 16.0 (15.3, 19.3) | −3.0 (−5.5, −2.8) |
| ALT, U/L | 15.0 (15.9, 25.1) | 14.0 (13.8, 23.0) | −6.7 (−13.2, −8.3) |
| Total bilirubin, mg/dL | 0.6 (0.6, 0.8) | 0.6 (0.6, 0.8) | 0.0 (−2.8, 0.5) |
| ALP, U/L | 49.5 (47.3, 55.7) | 51.0 (47.7, 55.0) | 3.0 (0.7, −1.3) |
| Total protein, g/dL | 7.3 (7.2, 7.4) | 7.2 (7.1, 7.3) | −1.4 (−1.4, −1.5) |
| Albumin, g/dL | 4.6 (4.6, 4.8) | 4.6 (4.4, 4.6) | −1.1 (−2.9, −3.3)∗ |
| Gamma GT, U/L | 18.0 (16.1, 29.3) | 15.0 (15.7, 24.7) | −16.7 (−2.3, −15.8) |
| BUN, mg/dL | 13.0 (12.3, 14.9) | 13.0 (12.0, 14.9) | 0.0 (−2.1, 0.5) |
| Creatinine, mg/dL | 0.8 (0.7, 0.8) | 0.8 (0.7, 0.8) | 0.0 (−1.2, −2.0) |
| Uric acid, mg/dL | 5.4 (4.9, 5.9) | 5.6 (4.9, 5.9) | 4.7 (−0.4, 0.4) |
1All values are medians (95% CIs). Results are from the per-protocol sample. ∗Between-group differences in the liver and renal factor were accessed by the paired sample t-test at p values < 0.01.