Table 2.
Estimation of the association between the four unique indicators of mental status over the ICU admission and both 28- and 90-day mortality
| Variable | 28-day mortality | 90-day mortality | ||||
|---|---|---|---|---|---|---|
| Unadjusted effect | Adjusted model 1* | Adjusted model 2^ | Unadjusted effect | Adjusted model 1* | Adjusted model 2^ | |
| Incident Delirium | 1.09 (0.85–1.41) | 1.02 (0.75–1.39) | 0.91 (0.68–1.21) | 1.18 (0.94–1.48) | 1.05 (0.79–1.38) | 0.92 (0.71–1.19) |
| Days of Delirium | 0.99 (0.96–1.02) | 1.00 (0.95–1.05) | 0.98 (0.94–1.02) | 1.01 (0.98–1.04) | 1.02 (0.98–1.07) | 0.99 (0.96–1.03) |
| Days of Coma | 1.06 (1.04–1.09) | 1.05 (1.02–1.08) | 1.19 (1.14–1.24) | 1.07 (1.04–1.09) | 1.05 (1.02–1.08) | 1.12 (1.08–1.16) |
| Days of Delirium or Coma | 1.02 (1.01–1.04) | 1.03 (1.003–1.05) | 1.07 (1.04–1.11) | 1.03 (1.02–1.05) | 1.03 (1.01–1.06) | 1.05 (1.02–1.08) |
Data is present as hazard ratios with their associated 95% confidence intervals. *Model 1 is adjusted to control for patient age, APACHE-II score at baseline, presence of sepsis, mechanical ventilation use, and haloperidol dose received, ^Model 2 is adjusted to control for patient age, APACHE-II score at baseline, presence of sepsis, mechanical ventilation use, haloperidol dose received, and ICU length of stay for each patient