Table 2.
Comparison of features for detecting diagnostic characters between DeSignate, BOLD’s Diagnostic Characters workbench utility [12], CAOS [13], and QUIDDICH [14]
| Features | DeSignate | BOLD | CAOS | QUIDDICH |
|---|---|---|---|---|
| Web interface | + | + | − | − |
| Command-line interface | + | − | + | + |
| Open source license | + | − | − | + |
| Requires no editing of input files | + | + | − | + |
| Free choice of nucleotide sequence alignment | + | + | + | + |
| Group selection with a (guide) tree | + | − | + | − |
| Free choice of the query and reference groups | + | − | + | + |
| Analysis of combined characters | + | − | + | − |
| Support for interpretation and validation | + | − | − | − |